8/3/2023 0 Comments Lock and key conceptThe following infographic presents the difference between Induced Fit and Lock and Key in a tabular form. The active site is not static in the induced fit model while it is static in lock and key model. The induced fit theory describes the binding of an enzyme and substrate that are not complementary while lock and key describe the binding of enzyme and substrate that are complementary. Induced fit and lock and key are two theories that explain the mode of an enzyme. What is the Difference Between Induced Fit and Lock and Key? They are really important to understand the binding of the substrate into an active site of an enzyme. ![]() Both theories explain the action mode of an enzyme.What are the Similarities Between Induced Fit and Lock and Key? According to this theory, confirmation of the active site modifies into a correct shape when the substrate binds. The induced fit is a theory that explains the binding of a substrate into an active site of an enzyme that does not have a correct conformation with that of the active site. Side by Side Comparison – Induced Fit vs Lock and Key in Tabular Form Similarities Between Induced Fit and Lock and Keyĥ. ![]() Two hypothesis namely, Induced Fit hypothesis and Lock and Key hypothesis explains this binding of the substrate into the enzyme. The substrate binds with the active site of the enzyme and then converts into the product. Therefore, they are specific for their substrates. Whereas, in the lock and key theory, the substrate and the active site of the enzyme are complementary in shape at the beginning.Įnzymes are catalysts of metabolic reactions. The key difference between Induced Fit and Lock and Key is that in induced fit theory, the binding of the substrate with the active site of the enzyme induces the modification of the shape of the active site into the complementary shape of the substrate.
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